Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.91 |
| ▸ | MAOB | P27338 | 6/20 | 0.91 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.91 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29766301 | 1.00 | MAOA (0.91) | MAOAMAOBCYP2A6CES1TSHR | |
| SCHEMBL163580 | 1.00 | MAOA (0.91) | MAOAMAOBCYP2A6CES1TSHR | |
| SCHEMBL4874556 | 1.00 | MAOA (0.91) | MAOAMAOBCYP2A6CES1TSHR | |
| SCHEMBL4573854 | 1.00 | MAOA (0.91) | MAOAMAOBCYP2A6CES1TSHR | |
| SCHEMBL20445627 | 1.00 | MAOA (0.91) | MAOAMAOBCYP2A6CES1TSHR | |
| SCHEMBL18716863 | 1.00 | MAOA (0.91) | MAOAMAOBCYP2A6CES1TSHR | |
| Ammonia Solution, Strong SCHEMBL28684723 | 0.98 | MAOA (0.87) | MAOAMAOBCYP2A6CES1TSHR | |
| SCHEMBL10456794 | 0.96 | MAOA (0.91) | MAOAMAOBCYP2A6CES1TSHR | |
| SCHEMBL44545 | 0.95 | MAOA (1.00) | MAOAMAOBCYP2A6CES1TSHR | |
| SCHEMBL29351871 | 0.95 | MAOA (1.00) | MAOAMAOBCYP2A6CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170066737-A1 | CYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170066737-A1 | CYCLIC COMPOUNDS | TLR4, TLR3, TLR1 | MAOA 4696/4885MAOB 4257/4885CYP2A6 3910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.