Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL850437 | 0.89 | HTT (0.62) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL17236532 | 0.78 | KMT2A (0.68) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL16357737 | 0.77 | MAPT (0.48) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL25253120 | 0.75 | KMT2A (0.77) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL31642809 | 0.75 | MAPT (0.74) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL25273344 | 0.75 | KMT2A (0.63) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25269062 | 0.74 | KMT2A (0.75) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2348940 | 0.72 | MEN1 (0.63) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL30976769 | 0.71 | HPGD (0.58) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL29130900 | 0.71 | POLB (0.64) | KMT2AMEN1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |