Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 15/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12163726 | 0.94 | KDM4E (0.38) | KDM4EHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL10194193 | 0.94 | KDM4E (0.38) | KDM4EHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL3602017 | 0.82 | ADORA2B (0.43) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL252404 | 0.82 | ADORA2B (0.43) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL381709 | 0.82 | ADORA2B (0.43) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL16357762 | 0.79 | ADORA1 (0.46) | KDM4EHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL12163724 | 0.78 | MAPT (0.46) | KDM4EHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL3304369 | 0.78 | KDM4E (0.34) | KDM4EHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL12163643 | 0.76 | ADORA1 (0.47) | KDM4EHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL14464210 | 0.76 | KDM4E (0.40) | KDM4EHSD17B10MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010072314-A1 | DIPEPTOID PRODRUGS AND THE USE THEREOF | BAYER SCHERING PHARMA AG (DE) | 2010-07-01 | — | — | WO | disclosed |