Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA4 | P22748 | 4/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18970643 | 0.84 | CA2 (0.40) | CA2CA1CA9CA12CA4 | |
| SCHEMBL12858792 | 0.84 | MEN1 (0.42) | CA2CA1CA9CA12CA4 | |
| SCHEMBL13073508 | 0.84 | SMN1; SMN2 (0.42) | CA2CA1CA9CA12CA4 | |
| SCHEMBL17447168 | 0.82 | MEN1 (0.41) | CA2CA1CA9CA12CA4 | |
| SCHEMBL26234016 | 0.81 | EPHX2 (0.42) | CA2CA1CA9CA12CA4 | |
| SCHEMBL26234035 | 0.81 | CA2 (0.39) | CA2CA1CA9CA12CA4 | |
| SCHEMBL8501843 | 0.81 | CA2 (0.40) | CA2CA1CA9CA12CA4 | |
| SCHEMBL16572453 | 0.81 | CA2 (0.37) | CA2CA1CA9CA12CA4 | |
| SCHEMBL12944853 | 0.81 | CA2 (0.37) | CA2CA1CA9CA12CA4 | |
| SCHEMBL8501834 | 0.81 | CA2 (0.37) | CA2CA1CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009061854-A2 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | VANDERBILT UNIVERSITY (US) | 2009-05-14 | — | — | WO | disclosed |