Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA4 | P22748 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16358264 | 0.84 | CA2 (0.39) | CA2CA12CA1CA4CA9 | |
| SCHEMBL14074912 | 0.79 | MEN1 (0.41) | CA2CA12CA1CA4CA9 | |
| SCHEMBL13581469 | 0.76 | PHF8 (0.46) | CA2CA12CA1CA4CA9 | |
| SCHEMBL4270081 | 0.76 | TSHR (0.46) | CA2CA12CA1CA4CA9 | |
| SCHEMBL525920 | 0.75 | — | — | |
| SCHEMBL10048529 | 0.74 | CASP2 (0.55) | CA2CA12CA1CA4CA9 | |
| SCHEMBL17276977 | 0.74 | TSHR (0.44) | CA2CA12CA1CA4CA9 | |
| SCHEMBL21049844 | 0.74 | ECE1 (0.42) | CA2CA12CA1CA4CA9 | |
| SCHEMBL19560737 | 0.74 | NAAA (0.47) | CA2CA12CA1CA4CA9 | |
| SCHEMBL15728323 | 0.74 | CA12 (0.46) | CA2CA12CA1CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017096430-A1 | HYDROXAMIC ACID-BASED COMPOUNDS | THE UNIVERSITY OF SYDNEY (AU) | 2017-06-15 | — | — | WO | disclosed |