Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PTH1R | Q03431 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16302564 | 0.92 | TYK2 (0.32) | TYK2GRIN2BPTH1R | |
| SCHEMBL16302523 | 0.92 | HTR1A (0.35) | — | |
| SCHEMBL16358600 | 0.90 | PTH1R (0.34) | PTH1R | |
| SCHEMBL16302606 | 0.86 | SCD5 (0.38) | — | |
| SCHEMBL16358598 | 0.86 | SYK (0.35) | SYK | |
| SCHEMBL16358383 | 0.85 | PTH1R (0.33) | PTH1R | |
| SCHEMBL16358771 | 0.85 | PTH1R (0.31) | GRIN2BPTH1R | |
| SCHEMBL16302457 | 0.84 | PTH1R (0.33) | PTH1R | |
| SCHEMBL16302310 | 0.83 | PTH1R (0.34) | PTH1R | |
| SCHEMBL16302445 | 0.83 | PTH1R (0.34) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |