SCHEMBL16358372 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	UBE2N	P61088	1/20	0.45

▸	ALDH1A1	P00352	2/20	0.41

▸	HSD11B1	P28845	1/20	0.41

▸	MEN1	O00255	2/20	0.41

▸	KMT2A	Q03164	2/20	0.41

▸	PKM	P14618	1/20	0.40

▸	PROKR1	Q8TCW9	2/20	0.40

▸	NPC1	O15118	1/20	0.39

▸	RAB9A	P51151	1/20	0.39

▸	AKR1C3	P42330	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL848229	0.91	LMNA (0.45)	UBE2NALDH1A1HSD11B1MEN1KMT2A
SCHEMBL848541	0.89	PDE2A (0.45)	UBE2NALDH1A1PKMPROKR1
SCHEMBL847334	0.86	MGLL (0.46)	ALDH1A1MEN1KMT2AAKR1C3
SCHEMBL847346	0.85	KMT2A (0.43)	ALDH1A1MEN1KMT2AAKR1C3
SCHEMBL13552166	0.85	MEN1 (0.42)	ALDH1A1MEN1KMT2AAKR1C3
SCHEMBL849916	0.85	KMT2A (0.42)	ALDH1A1MEN1KMT2AAKR1C3
SCHEMBL847373	0.85	MAPT (0.44)	ALDH1A1MEN1KMT2AAKR1C3
SCHEMBL849574	0.83	STS (0.46)	ALDH1A1MEN1KMT2A
SCHEMBL848383	0.83	MEN1 (0.41)	ALDH1A1MEN1KMT2A
SCHEMBL848801	0.83	PTH1R (0.42)	ALDH1A1HSD11B1MEN1KMT2AAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010126030-A1	SPIROIMIDAZOLONE DERIVATIVE	中外製薬株式会社 (JP)	2010-11-04	—	—	WO	disclosed