Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 5/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.61 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17066704 | 0.91 | GPR55 (0.86) | GPR55ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL17066647 | 0.89 | GPR55 (0.82) | GPR55ALDH1A1LMNASMN1; SMN2ALOX12 | |
| SCHEMBL13454592 | 0.89 | GPR55 (1.00) | GPR55ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL17066573 | 0.88 | GPR55 (0.77) | GPR55ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL17066564 | 0.88 | GPR55 (0.77) | GPR55ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL13454367 | 0.88 | ALDH1A1 (0.68) | GPR55ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL17066584 | 0.88 | GPR55 (0.80) | GPR55ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL16358904 | 0.88 | GPR55 (0.80) | GPR55ALDH1A1LMNASMN1; SMN2ALOX12 | |
| SCHEMBL17066578 | 0.87 | GPR55 (0.76) | GPR55ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL13454380 | 0.87 | KMT2A (0.70) | GPR55ALDH1A1MAPTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| WO-2011022393-A2 | PHOSPHATIDYLCHOLINE TRANSFER PROTEIN INHIBITORS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2011-02-24 | — | — | WO | disclosed |