Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 6/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16302457 | 0.90 | PTH1R (0.33) | PTH1RAR | |
| SCHEMBL16302445 | 0.88 | PTH1R (0.34) | PTH1RAR | |
| SCHEMBL16302310 | 0.88 | PTH1R (0.34) | PTH1R | |
| SCHEMBL13064557 | 0.85 | PTH1R (0.40) | PTH1RKMOTRPM8AR | |
| SCHEMBL850838 | 0.85 | PTH1R (0.40) | PTH1RKMOTRPM8AR | |
| SCHEMBL16358983 | 0.85 | PTH1R (0.48) | PTH1RAR | |
| SCHEMBL16358600 | 0.82 | PTH1R (0.34) | PTH1R | |
| SCHEMBL16358383 | 0.80 | PTH1R (0.33) | PTH1RKMO | |
| SCHEMBL16358986 | 0.79 | AR (0.36) | PTH1RKMOAR | |
| SCHEMBL16358349 | 0.79 | TYK2 (0.32) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |