Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 20/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 18/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2071422 | 0.90 | OPRD1 (0.75) | OPRD1KCNH2CYP2D6OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL2073195 | 0.89 | OPRD1 (0.74) | OPRD1KCNH2CYP2D6OPRK1OPRM1 | |
| SCHEMBL471687 | 0.79 | OPRD1 (0.54) | OPRD1KCNH2CYP2D6OPRK1OPRM1 | |
| SCHEMBL16350075 | 0.78 | OPRD1 (0.78) | OPRD1KCNH2CYP2D6OPRK1OPRM1 | |
| SCHEMBL467302 | 0.77 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRK1OPRM1 | |
| SCHEMBL16300059 | 0.76 | OPRD1 (0.70) | OPRD1KCNH2CYP2D6OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL2071898 | 0.76 | OPRD1 (0.98) | OPRD1KCNH2CYP2D6OPRK1OPRM1 | |
| SCHEMBL471421 | 0.75 | OPRD1 (0.87) | OPRD1KCNH2CYP2D6OPRK1OPRM1 | |
| SCHEMBL471278 | 0.74 | OPRD1 (0.80) | OPRD1KCNH2CYP2D6OPRK1OPRM1 | |
| SCHEMBL471448 | 0.73 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033299-A2 | USE OF N-CONTAINING SPIROCOMPOUNDS FOR THE ENHANCEMENT OF COGNITIVE FUNCTION | ADOLOR CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |