Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GLB1 | P16278 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | GBA1 | P04062 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203309 | 0.86 | CYP1A2 (0.46) | CYP1A2GLB1LMNAMAPK1HTT | |
| SCHEMBL25268467 | 0.84 | — | — | |
| SCHEMBL28403402 | 0.83 | CA1 (0.42) | GLB1LMNAMAPK1MAPTGBA1 | |
| SCHEMBL17625306 | 0.80 | CYP1A2 (0.40) | CYP1A2GLB1LMNAMAPK1HTT | |
| SCHEMBL12166923 | 0.78 | FUCA1 (0.44) | CYP1A2GLB1LMNAMAPK1HTT | |
| SCHEMBL17827044 | 0.78 | LMNA (0.44) | CYP1A2GLB1LMNAMAPK1HTT | |
| SCHEMBL12166845 | 0.78 | CYP1A2 (0.43) | CYP1A2GLB1LMNAMAPK1HTT | |
| SCHEMBL10158419 | 0.78 | LMNA (0.44) | CYP1A2GLB1LMNAMAPK1HTT | |
| SCHEMBL9512947 | 0.78 | LSS (0.47) | CYP1A2LMNAMAPK1HTTLSS | |
| SCHEMBL10158088 | 0.77 | CYP1A2 (0.42) | CYP1A2GLB1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054406-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |