Sugi Predict

Sugi Predict / Compounds / SCHEMBL10158419

SCHEMBL10158419

SCHEMBL10158419

CCCCC1CCC(C)C(O)C1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ HTT P42858 1/20 0.44
▸ CYP1A2 P05177 1/20 0.43
▸ LSS P48449 2/20 0.37
▸ GLB1 P16278 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ TLR4 O00206 1/20 0.36
▸ POLB P06746 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ GBA1 P04062 1/20 0.34
▸ TRPV1 Q8NER1 4/20 0.33
▸ CNR1 P21554 2/20 0.33
▸ CNR2 P34972 2/20 0.33
▸ CA1 P00915 2/20 0.33
▸ CA2 P00918 2/20 0.33
▸ CA4 P22748 2/20 0.33
▸ FUCA1 P04066 1/20 0.33
▸ NAAA Q02083 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17827044 1.00 LMNA (0.44) LMNAMAPK1HTTCYP1A2LSS
SCHEMBL10053743 0.88 CA1 (0.39) LMNAMAPK1HTTMAPTGBA1
SCHEMBL21773610 0.88 CA1 (0.39) LMNAMAPK1HTTMAPTGBA1
SCHEMBL12279488 0.88 CA1 (0.39) LMNAMAPK1HTTMAPTGBA1
SCHEMBL12166491 0.84 LMNA (0.44) LMNAMAPK1HTTCYP1A2LSS
SCHEMBL20203309 0.83 CYP1A2 (0.46) LMNAMAPK1HTTCYP1A2LSS
SCHEMBL11903679 0.81 CYP1A2 (0.48) LMNAMAPK1HTTCYP1A2LSS
SCHEMBL12166845 0.80 CYP1A2 (0.43) LMNAMAPK1HTTCYP1A2LSS
SCHEMBL19197712 0.79 CA1 (0.39) CA1CA2CA4
SCHEMBL12166548 0.79 CA1 (0.39) CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151676-A1 SILANE FUNCTIONAL STABILIZERS FOR EXTENDING LONG-TERM ELECTRICAL POWER CABLE PERFORMANCE SOUTHWIRE COMPANY, LLC (US) 2024-07-18 — — WO disclosed
US-20230360821-A1 SILANE FUNCTIONAL STABILIZERS FOR EXTENDING LONG-TERM ELECTRICAL POWER CABLE PERFORMANCE AMINDON INC. 2023-11-09 — — US disclosed
US-20230360821-A1 SILANE FUNCTIONAL STABILIZERS FOR EXTENDING LONG-TERM ELECTRICAL POWER CABLE PERFORMANCE AMINDON INC. 2023-11-09 — — US disclosed
US-11749422-B2 Silane functional stabilizers for extending long-term electrical power cable performance NOVINIUM, LLC (US) 2023-09-05 — — US disclosed
US-11749422-B2 Silane functional stabilizers for extending long-term electrical power cable performance NOVINIUM, LLC (US) 2023-09-05 — — US disclosed
US-20210017384-A1 SILANE FUNCTIONAL STABILIZERS FOR EXTENDING LONG-TERM ELECTRICAL POWER CABLE PERFORMANCE MADISON ELECTRIC PRODUCTS, LLC 2021-01-21 — — US disclosed
US-20170342345-A1 TREATMENT COMPOSITIONS PROCTER & GAMBLE (US) 2017-11-30 — — US disclosed
US-20170327648-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2017-11-16 — — US disclosed
US-20170327647-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2017-11-16 — — US disclosed
US-20170283735-A1 CONTROLLED RELEASE DUAL WALLED MICROCAPSULES ENCAPSYS, LLC (US) 2017-10-05 — — US disclosed
US-9012497-B2 Cyclohexyl carbamate compounds as active anti-cellulite ingredients SYMRISE AG (DE) 2015-04-21 — — US disclosed
US-20150093350-A1 ORGANOSILICONES PROCTER & GAMBLE (US) 2015-04-02 — — US disclosed
US-20140033448-A1 ORGANOSILICONES THE PROCTER & GAMBLE COMPANY (US) 2014-02-06 — — US disclosed
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2013-06-20 — — US disclosed
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2013-06-20 — — US disclosed
US-20130137710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE AG (DE) 2013-05-30 — — US disclosed
US-20130137710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE AG (DE) 2013-05-30 — — US disclosed
US-20120052038-A1 Organosilicones THE PROCTER & GAMBLE COMPANY 2012-03-01 — — US disclosed
EP-2389922-A1 Cyclohexyl carbamate compounds as anti-ageing actives Symrise AG (DE) 2011-11-30 — — EP disclosed
EP-1829535-A2 Tissue factor antagonists and methods of use thereof Tanox, Inc. (US) 2007-09-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150093350-A1 ORGANOSILICONES NISCH, XRCC6, RAD50 LMNA 1605/4885MAPK1 3987/4885HTT 1207/4885
US-20120052038-A1 Organosilicones NISCH, XRCC6, RAD50 LMNA 1605/4885MAPK1 3987/4885HTT 1207/4885
US-20170327648-A1 SILICONE COMPOUNDS SMCHD1, SMS, SGMS1 LMNA 18/4885MAPK1 3468/4885HTT 2089/4885
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES CBR1, CYP2A13, CBR3 LMNA 1211/4885MAPK1 3313/4885HTT 1529/4885
US-20170283735-A1 CONTROLLED RELEASE DUAL WALLED MICROCAPSULES MYADM, MCHR2, MCHR1 LMNA 1041/4885MAPK1 4578/4885HTT 88/4885
US-20130137710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS CBR1, NCOR2, CECR2 LMNA 2360/4885MAPK1 4032/4885HTT 3466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.