Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19500429 | 0.89 | ALDH1A1 (0.50) | EPHX1SMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL38654908 | 0.88 | SMN1; SMN2 (0.62) | EPHX1SMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL24793189 | 0.85 | SMN1; SMN2 (0.50) | EPHX1SMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL24262379 | 0.85 | ALDH1A1 (0.50) | EPHX1SMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL30093387 | 0.85 | SMN1; SMN2 (0.50) | EPHX1SMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL13847041 | 0.85 | ALDH1A1 (0.54) | EPHX1SMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL24243983 | 0.83 | SMN1; SMN2 (0.52) | EPHX1SMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL21224801 | 0.83 | SMN1; SMN2 (0.52) | EPHX1SMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL17035294 | 0.83 | MEN1 (0.44) | EPHX1SMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL3219761 | 0.83 | SMN1; SMN2 (0.52) | EPHX1SMN1; SMN2ALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160237208-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | UNIV VANDERBILT (US) | 2016-08-18 | — | — | US | disclosed |
| WO-2011082432-A1 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | VANDERBILT UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |