Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 5/20 | 0.54 |
| ▸ | NMT2 | O60551 | 4/20 | 0.54 |
| ▸ | NPY4R | P50391 | 7/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.49 |
| ▸ | NPY1R | P25929 | 5/20 | 0.49 |
| ▸ | NPY2R | P49146 | 3/20 | 0.49 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16359357 | 1.00 | NMT1 (0.54) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL13363643 | 0.94 | NMT2 (0.49) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL26168056 | 0.93 | NMT2 (0.47) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL19772469 | 0.93 | NMT2 (0.47) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL10592847 | 0.92 | NMT1 (0.50) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL3054641 | 0.90 | TLR2 (0.60) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL29395483 | 0.88 | TLR2 (0.55) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL10046596 | 0.88 | TLR2 (0.63) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL18862080 | 0.87 | NPY4R (0.48) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL26890960 | 0.86 | NMT1 (0.52) | NMT1NMT2NPY4RNPY5RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053548-A2 | PTHR1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |