Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 6/20 | 0.52 |
| ▸ | NMT2 | O60551 | 5/20 | 0.52 |
| ▸ | NPY4R | P50391 | 6/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.43 |
| ▸ | NPY1R | P25929 | 4/20 | 0.43 |
| ▸ | NPY2R | P49146 | 2/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16359306 | 0.86 | NMT1 (0.54) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL16359357 | 0.86 | NMT1 (0.54) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL26888060 | 0.85 | NMT1 (0.52) | NMT1NMT2 | |
| SCHEMBL26167562 | 0.83 | FURIN (0.36) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL10592847 | 0.82 | NMT1 (0.50) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL26168056 | 0.81 | NMT2 (0.47) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL19772469 | 0.81 | NMT2 (0.47) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL10046596 | 0.80 | TLR2 (0.63) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL3054641 | 0.80 | TLR2 (0.60) | NMT1NMT2NPY4RNPY5RNPY1R | |
| SCHEMBL13363643 | 0.80 | NMT2 (0.49) | NMT1NMT2NPY4RNPY5RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225661-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-23 | — | — | WO | disclosed |