Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRB2 | P62993 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CHRND | Q07001 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16358941 | 1.00 | ACE (0.46) | ACEERAP2ERAP1LNPEPMME | |
| SCHEMBL16507942 | 0.91 | ACE (0.39) | ACENPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL16358940 | 0.91 | ACE (0.38) | ACE | |
| SCHEMBL13363654 | 0.87 | ACE (0.49) | ACEERAP2ERAP1LNPEPMME | |
| SCHEMBL16507827 | 0.85 | ACE (0.49) | ACELNPEPMMECPA1ACE2 | |
| SCHEMBL31020877 | 0.85 | ACE (0.47) | ACENPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL16507899 | 0.78 | PTPN1 (0.44) | ACENPY4R | |
| SCHEMBL11012174 | 0.78 | ACE (0.43) | ACEERAP2ERAP1LNPEPMME | |
| SCHEMBL7281103 | 0.77 | PARP1 (0.50) | ERAP2ERAP1LNPEP | |
| SCHEMBL13363651 | 0.77 | ACE (0.46) | ACEMMECPA1ACE2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053548-A2 | PTHR1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |