Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 5/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 1/20 | 0.37 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31020877 | 0.90 | ACE (0.47) | ACEGRB2NPY4RKISS1R | |
| SCHEMBL16507827 | 0.90 | ACE (0.49) | ACEMMECPA1ACE2REN | |
| SCHEMBL16358941 | 0.87 | ACE (0.46) | ACEMMECPA1ACE2GRB2 | |
| SCHEMBL16359347 | 0.87 | ACE (0.46) | ACEMMECPA1ACE2GRB2 | |
| SCHEMBL8252710 | 0.84 | REN (0.38) | ACEGRB2REN | |
| SCHEMBL16507899 | 0.83 | PTPN1 (0.44) | ACERENNPY4R | |
| SCHEMBL30670300 | 0.81 | LNPEP (0.54) | ACEMMECPA1ACE2LNPEP | |
| SCHEMBL16507942 | 0.80 | ACE (0.39) | ACENPY4R | |
| SCHEMBL11014003 | 0.80 | REN (0.47) | ACEMMECPA1ACE2REN | |
| SCHEMBL16507850 | 0.80 | NPY4R (0.47) | ACERENNPY4RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053548-A2 | PTHR1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |