Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.73 |
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.64 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4993214 | 0.98 | HRH3 (0.73) | LTA4HPTGS1PTGS2HRH3ATM | |
| SCHEMBL491609 | 0.98 | MEN1 (0.71) | LTA4HPTGS1PTGS2HRH3ATM | |
| SCHEMBL4457910 | 0.95 | LTA4H (0.76) | LTA4HPTGS1PTGS2HRH3MEN1 | |
| SCHEMBL4465869 | 0.93 | HRH3 (0.75) | LTA4HPTGS1PTGS2HRH3ATM | |
| SCHEMBL2968936 | 0.93 | HRH3 (0.75) | LTA4HPTGS1PTGS2HRH3ATM | |
| Hydrochloric Acid SCHEMBL736843 | 0.92 | HRH3 (0.73) | LTA4HPTGS1PTGS2HRH3ATM | |
| Oxalic Acid SCHEMBL5856171 | 0.90 | HRH3 (0.74) | HRH3L3MBTL1MEN1HTTKMT2A | |
| SCHEMBL56495 | 0.89 | LTA4H (0.90) | LTA4HPTGS1PTGS2HRH3KCNH2 | |
| SCHEMBL23724061 | 0.88 | LTA4H (0.87) | LTA4HPTGS1PTGS2HRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL15254264 | 0.88 | LTA4H (0.87) | LTA4HPTGS1PTGS2HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005089764-A9 | CARBOLINE DERIVATIVES USEFUL IN THE INHIBITION OF ANGIOGENESIS | PTC THERAPEUTICS INC (US) | 2007-09-13 | — | — | WO | disclosed |