Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.87 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.87 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.87 |
| ▸ | PSMB1 | P20618 | 7/20 | 0.70 |
| ▸ | PSMB5 | P28074 | 7/20 | 0.70 |
| ▸ | PSMB2 | P49721 | 6/20 | 0.70 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937460 | 1.00 | LTA4H (0.87) | LTA4HPTGS1PTGS2PSMB1PSMB5 | |
| Hydrochloric Acid SCHEMBL3997911 | 0.98 | LTA4H (0.84) | LTA4HPTGS1PTGS2PSMB1PSMB5 | |
| SCHEMBL56495 | 0.98 | LTA4H (0.90) | LTA4HPTGS1PTGS2PSMB1PSMB5 | |
| Hydrochloric Acid SCHEMBL15254264 | 0.96 | LTA4H (0.87) | LTA4HPTGS1PTGS2PSMB1PSMB5 | |
| SCHEMBL4465869 | 0.91 | HRH3 (0.75) | LTA4HPTGS1PTGS2HRH3KCNH2 | |
| SCHEMBL2968936 | 0.91 | HRH3 (0.75) | LTA4HPTGS1PTGS2HRH3KCNH2 | |
| SCHEMBL4993214 | 0.90 | HRH3 (0.73) | LTA4HPTGS1PTGS2HRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL736843 | 0.90 | HRH3 (0.73) | LTA4HPTGS1PTGS2HRH3KCNH2 | |
| SCHEMBL4457910 | 0.89 | LTA4H (0.76) | LTA4HPTGS1PTGS2HRH3KCNH2 | |
| SCHEMBL3398830 | 0.89 | LTA4H (0.75) | LTA4HPTGS1PTGS2PSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246920-A1 | TRIAZOLE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | KING'S COLLEGE LONDON (GB) | 2024-07-25 | — | — | US | disclosed |
| EP-4100400-A1 | TRIAZOLE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | Kings College London (GB) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021156636-A1 | TRIAZOLE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | KING'S COLLEGE LONDON (GB) | 2021-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246920-A1 | TRIAZOLE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | RIF1, NAT1, POLR1C | LTA4H 2619/4885PTGS1 2856/4885PTGS2 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.