Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | CCR9 | P51686 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12290954 | 0.81 | MAPT (0.52) | MAPTSMN1; SMN2HTTCCR9RAB9A | |
| SCHEMBL4844927 | 0.81 | MAPT (0.70) | MAPTSMN1; SMN2HTTCCR9RAB9A | |
| SCHEMBL48235 | 0.81 | MAPT (0.52) | MAPTSMN1; SMN2HTTCCR9RAB9A | |
| SCHEMBL8011466 | 0.78 | MAPT (0.50) | MAPTSMN1; SMN2HTTCCR9RAB9A | |
| SCHEMBL28400194 | 0.77 | HTT (0.67) | MAPTSMN1; SMN2HTTRAB9AALDH1A1 | |
| SCHEMBL12291074 | 0.75 | MAPT (0.47) | MAPTSMN1; SMN2HTTCCR9RAB9A | |
| SCHEMBL24102358 | 0.74 | DGAT1 (0.52) | MAPTSMN1; SMN2ALDH1A1POLBKDM4E | |
| SCHEMBL7662781 | 0.73 | NR4A2 (0.49) | MAPTSMN1; SMN2HTTRAB9AALDH1A1 | |
| SCHEMBL1255660 | 0.73 | PTGS2 (0.51) | MAPTSMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL29709928 | 0.73 | PTGS2 (0.51) | MAPTSMN1; SMN2HTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011107494-A1 | NOVEL AROMATIC GLYCOSIDE DERIVATIVES, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND THE USE THEREOF | SANOFI (FR) | 2011-09-09 | — | — | WO | disclosed |