SCHEMBL1636025

SCHEMBL1636025

C=C(C(N)=O)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
F2 P00734 2/20 0.34
PRSS1 P07477 2/20 0.34
PRSS2 P07478 2/20 0.34
PRSS3 P35030 2/20 0.34
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1634219 0.93 THRB (0.46) THRBF2PRSS1PRSS2PRSS3
SCHEMBL28631834 0.91 THRB (0.50) THRBF2PRSS1PRSS2PRSS3
SCHEMBL1634210 0.84 TDP1 (0.36) TDP1
SCHEMBL27952731 0.83 TDP1 (0.32) TDP1
SCHEMBL15413473 0.78
SCHEMBL1635423 0.77 THRB (0.44) THRB
SCHEMBL1635663 0.73
Heptafluorobutyramide SCHEMBL809135 0.73 THRB (0.43) THRBF2PRSS1PRSS2PRSS3
SCHEMBL28541637 0.72
Heptafluorobutyramide SCHEMBL4827051 0.70 THRB (0.42) THRBF2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8378016-B2 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-19 US disclosed
US-20110165519-A1 RESIN SUITABLE FOR AN ACID GENERATOR AND A CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION CONTAINING THE SAME ANDO NOBUO 2011-07-07 US disclosed
US-7932334-B2 Resin suitable for an acid generator SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-26 US disclosed
US-20070149702-A1 Resin suitable for an acid generator and a chemically amplified positive resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-06-28 US disclosed