SCHEMBL1635663

SCHEMBL1635663

C=C(C(N)=O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1634210 0.77 TDP1 (0.36)
SCHEMBL3880777 0.73
SCHEMBL973725 0.73 CA2 (0.33)
SCHEMBL14028208 0.73
SCHEMBL1636025 0.73 THRB (0.37)
SCHEMBL9455389 0.71
SCHEMBL864818 0.71
SCHEMBL2776908 0.71
SCHEMBL203037 0.71
SCHEMBL1930049 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113683726-B Polymer for fuel cell proton exchange membrane and preparation method thereof 常熟三爱富中昊化工新材料有限公司 2022-10-14 CN claimed
CN-113683726-A Polymer for fuel cell proton exchange membrane and preparation method thereof 常熟三爱富中昊化工新材料有限公司 2021-11-23 CN claimed
CN-119409645-A USP inhibitor, preparation method and application thereof 重庆华森英诺生物科技有限公司 2025-02-11 CN disclosed
EP-3668845-B1 HERBICIDALLY ACTIVE 3-PHENYL-5-TRIFLUORMETHYLISOXAZOLIN-5-CARBOXAMIDES OF CYCLOPENTYL CARBOXYLIC ACIDS AND ESTERS BAYER AG (DE) 2024-06-26 EP disclosed
CN-111164077-B Herbicidal 3-phenyl-5-trifluoromethyl isoxazoline-5-carboxamides of cyclopentylcarboxylic acids and esters thereof 拜耳公司 2023-12-19 CN disclosed
US-20230234921-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF ASCLETIS BIOSCIENCE CO., LTD. (CN) 2023-07-27 US disclosed
EP-4214197-A1 SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS Nura Bio, Inc. (US) 2023-07-26 EP disclosed
CN-113683726-B Polymer for fuel cell proton exchange membrane and preparation method thereof 常熟三爱富中昊化工新材料有限公司 2022-10-14 CN disclosed
WO-2022060812-A1 SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS NURA BIO, INC. (US) 2022-03-24 WO disclosed
CN-113683726-A Polymer for fuel cell proton exchange membrane and preparation method thereof 常熟三爱富中昊化工新材料有限公司 2021-11-23 CN disclosed
US-20200369630-A1 HERBICIDALLY ACTIVE 3-PHENYL-5-TRIFLUOROMETHYLISOXAZOLINE-5-CARBOXAMIDES OF CYCLOPENTYLCARBOXYLIC ACIDS AND ESTERS BAYER AKTIENGESELLSCHAFT (DE) 2020-11-26 US disclosed
CN-101003591-B Resin suitable for an acid generator and a chemically amplified positive resist composition containing the same SUMITOMO CHEMICAL CO 2011-08-17 CN disclosed
WO-2011090760-A1 HETEROARYL COMPOUNDS AND USES THEREOF AVILA THERAPEUTICS, INC. (US) 2011-07-28 WO disclosed
US-20110165519-A1 RESIN SUITABLE FOR AN ACID GENERATOR AND A CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION CONTAINING THE SAME ANDO NOBUO 2011-07-07 US disclosed
US-7932334-B2 Resin suitable for an acid generator SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-26 US disclosed
EP-2139874-A2 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL Sumitomo Chemical Company, Limited (JP) 2010-01-06 EP disclosed
WO-2009082697-A1 HCV PROTEASE INHIBITORS AND USES THEREOF AVILA THERAPEUTICS, INC. (US) 2009-07-02 WO disclosed
WO-2008126665-A2 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-23 WO disclosed
CN-101003591-A Resin suitable for an acid generator and a chemically amplified positive resist composition containing the same SUMITOMO CHEMICAL CO (JP) 2007-07-25 CN disclosed
US-20070149702-A1 Resin suitable for an acid generator and a chemically amplified positive resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-06-28 US disclosed