Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSK | P41240 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA7 | P43166 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TPH1 | P17752 | 1/20 | 0.36 |
| ▸ | GRB2 | P62993 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12155049 | 0.89 | SLC7A5 (0.57) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL826519 | 0.89 | SLC7A5 (0.57) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL15081041 | 0.86 | ALDH1A1 (0.46) | CSKSLC7A5ALPIPKMPTGS1 | |
| SCHEMBL19733539 | 0.81 | SLC7A5 (0.46) | CSKSLC7A5ALPIPKMPTGS1 | |
| SCHEMBL7471913 | 0.77 | ALDH1A1 (0.52) | CA12CA1CA2CA7TDP1 | |
| SCHEMBL14355742 | 0.77 | SLC7A5 (0.48) | CSKSLC7A5ALPIPKMPTGS1 | |
| SCHEMBL14559931 | 0.77 | SLC7A5 (0.48) | CSKSLC7A5ALPIPKMPTGS1 | |
| SCHEMBL9780166 | 0.77 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL26747607 | 0.75 | ITGB3 (0.41) | CSKSLC7A5ALPIPKMPTGS1 | |
| SCHEMBL12028154 | 0.75 | SLC7A5 (0.53) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012166560-A1 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACID LINKED DOLASTATIN DERIVATIVES | AMBRX, INC. (US) | 2012-12-06 | — | — | WO | disclosed |