Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19528477 | 0.84 | ARG1 (0.37) | MEN1APEX1KMT2AARG1ARG2 | |
| SCHEMBL12526523 | 0.82 | ALDH1A1 (0.39) | ARG1ARG2KIF11ALDH1A1ALOX15 | |
| SCHEMBL12819514 | 0.82 | ALDH1A1 (0.39) | ARG1ARG2KIF11ALDH1A1ALOX15 | |
| SCHEMBL16830417 | 0.79 | ARG1 (0.43) | ARG1ARG2GRIK1GRIK2KIF11 | |
| SCHEMBL936034 | 0.79 | GRIN2D (0.43) | GRIK1GRIK2ALDH1A1ANPEP | |
| SCHEMBL16830406 | 0.79 | ARG1 (0.43) | ARG1ARG2GRIK1GRIK2KIF11 | |
| SCHEMBL826528 | 0.77 | ALDH1A1 (0.45) | ARG1ARG2ALDH1A1ALOX15NOS1 | |
| SCHEMBL21335955 | 0.77 | ALDH1A1 (0.45) | ARG1ARG2ALDH1A1ALOX15NOS1 | |
| SCHEMBL25662308 | 0.76 | GRIN2D (0.38) | KMT2AGRIK1GRIK2ALDH1A1ALOX15 | |
| SCHEMBL25660587 | 0.76 | GRIN2D (0.38) | KMT2AGRIK1GRIK2ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020082057-A1 | INTERLEUKIN-10 POLYPEPTIDE CONJUGATES, DIMERS THEREOF, AND THEIR USES | AMBRX, INC. (US) | 2020-04-23 | — | — | WO | disclosed |
| WO-2012166560-A1 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACID LINKED DOLASTATIN DERIVATIVES | AMBRX, INC. (US) | 2012-12-06 | — | — | WO | disclosed |