Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 10/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781277 | 0.81 | GRIN2B (0.49) | GRIN2BRENGRIN1MEN1KMT2A | |
| SCHEMBL28007343 | 0.80 | GRIN2B (0.42) | GRIN2BRENGRIN1MEN1KMT2A | |
| SCHEMBL12526803 | 0.78 | GRIN2B (0.46) | GRIN2BRENGRIN1GLO1MCL1 | |
| SCHEMBL15417983 | 0.76 | GRIN2B (0.45) | GRIN2BRENGRIN1MEN1KMT2A | |
| SCHEMBL16471687 | 0.73 | REN (0.51) | GRIN2BRENBRD4 | |
| SCHEMBL5695751 | 0.73 | MEN1 (0.57) | GRIN2BMEN1KMT2ANPC1GAA | |
| SCHEMBL1050483 | 0.68 | REN (0.42) | GRIN2BRENGLO1MCL1 | |
| SCHEMBL27038040 | 0.66 | MEN1 (0.51) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL31473662 | 0.66 | MEN1 (0.51) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL27951558 | 0.65 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012124775-A1 | NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND | 田辺三菱製薬株式会社 (JP) | 2012-09-20 | — | — | WO | disclosed |