Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28751183 | 0.88 | TP53 (0.47) | HPGDTDP1LMNASMN1; SMN2NPC1 | |
| SCHEMBL4918506 | 0.84 | HPGD (0.61) | HPGDTDP1LMNASMN1; SMN2NPC1 | |
| Formic Acid SCHEMBL27625575 | 0.83 | BACE1 (0.46) | HPGDTDP1LMNASMN1; SMN2NPC1 | |
| SCHEMBL7406512 | 0.82 | HPGD (0.79) | HPGDTDP1LMNASMN1; SMN2NPC1 | |
| SCHEMBL3610292 | 0.80 | HPGD (0.56) | HPGDTDP1LMNASMN1; SMN2NPC1 | |
| SCHEMBL27774013 | 0.78 | GSK3B (0.47) | HPGDLMNASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL13640725 | 0.77 | CYP3A4 (0.41) | HPGDTDP1LMNAMEN1KMT2A | |
| SCHEMBL2566192 | 0.76 | HPGD (0.69) | HPGDTDP1LMNASMN1; SMN2NPC1 | |
| Diethyltoluamide SCHEMBL29976 | 0.76 | HPGD (1.00) | HPGDTDP1LMNASMN1; SMN2NPC1 | |
| SCHEMBL29386132 | 0.76 | HPGD (0.69) | HPGDTDP1LMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042506-B1 | SUBSTITUTED PHENYLETHYNYL GOLD-NITROGENATED HETEROCYCLIC CARBENE COMPLEX | UBE INDUSTRIES (JP) | 2012-12-19 | — | — | EP | disclosed |
| US-7932398-B2 | Substituted phenylethynylgold-nitrogen-containing heterocyclic carbene complex | UBE INDUSTRIES, LTD. (JP) | 2011-04-26 | — | — | US | disclosed |
| US-20090234130-A1 | SUBSTITUTED PHENYLETHYNYLGOLD-NITROGEN-CONTAINING HETEROCYCLIC CARBENE COMPLEX | UBE INDUSTRIES, LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-2042506-A1 | SUBSTITUTED PHENYLETHYNYL GOLD-NITROGENATED HETEROCYCLIC CARBENE COMPLEX | Ube Industries, Ltd. (JP) | 2009-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234130-A1 | SUBSTITUTED PHENYLETHYNYLGOLD-NITROGEN-CONTAINING HETEROCYCLIC CARBENE COMPLEX | CCRL2, CCNL2, ATXN2L | HPGD 3064/4885TDP1 4727/4885LMNA 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.