Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | MLYCD | O95822 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2566192 | 0.92 | HPGD (0.69) | HPGDTDP1ALDH1A1LMNATSHR | |
| SCHEMBL29386132 | 0.92 | HPGD (0.69) | HPGDTDP1ALDH1A1LMNATSHR | |
| SCHEMBL2854780 | 0.91 | HPGD (0.67) | HPGDTDP1ALDH1A1LMNATSHR | |
| SCHEMBL16005309 | 0.91 | HPGD (0.67) | HPGDTDP1ALDH1A1LMNATSHR | |
| SCHEMBL11506268 | 0.89 | HPGD (0.77) | HPGDTDP1ALDH1A1LMNATSHR | |
| Diethyltoluamide SCHEMBL29374310 | 0.88 | HPGD (1.00) | HPGDTDP1ALDH1A1LMNATSHR | |
| Diethyltoluamide SCHEMBL29976 | 0.88 | HPGD (1.00) | HPGDTDP1ALDH1A1LMNATSHR | |
| SCHEMBL1867393 | 0.88 | HPGD (0.69) | HPGDTDP1ALDH1A1LMNATSHR | |
| SCHEMBL4300450 | 0.88 | HPGD (0.69) | HPGDTDP1ALDH1A1LMNATSHR | |
| Diethyltoluamide SCHEMBL3797487 | 0.88 | HPGD (1.00) | HPGDTDP1ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813525-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996028427-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1996-09-19 | — | — | WO | disclosed |
| US-4665410-A | THERMOGRAPHY | RICOH COMPANY, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4663641-A | LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES | RICOH COMPANY, LTD. (JP) | 1987-05-05 | — | — | US | disclosed |
| US-4613878-A | DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS | RICOH COMPANY, LTD. (JP) | 1986-09-23 | — | — | US | disclosed |
| US-4133833-A | TITANIUM CATALYSTS ONE STEP | PFIZER INC. (US) | 1979-01-09 | — | — | US | disclosed |