Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860819 | 0.85 | RIPK1 (0.61) | LMNARIPK1KDM4EL3MBTL1AOC3 | |
| SCHEMBL4837244 | 0.85 | RIPK1 (0.61) | LMNARIPK1KDM4EL3MBTL1AOC3 | |
| SCHEMBL11828179 | 0.85 | RIPK1 (0.61) | LMNARIPK1KDM4EL3MBTL1AOC3 | |
| SCHEMBL8710104 | 0.85 | RIPK1 (0.61) | LMNARIPK1KDM4EL3MBTL1AOC3 | |
| SCHEMBL3081755 | 0.83 | RIPK1 (0.64) | LMNARIPK1KDM4EL3MBTL1AOC3 | |
| SCHEMBL5185803 | 0.83 | RIPK1 (0.64) | LMNARIPK1KDM4EL3MBTL1AOC3 | |
| SCHEMBL7417534 | 0.82 | HRH1 (0.68) | LMNARIPK1KDM4EL3MBTL1AOC3 | |
| SCHEMBL4281797 | 0.82 | HRH1 (0.68) | LMNARIPK1KDM4EL3MBTL1AOC3 | |
| Hydrochloric Acid SCHEMBL326015 | 0.80 | HRH1 (0.65) | LMNARIPK1KDM4EL3MBTL1AOC3 | |
| SCHEMBL15355244 | 0.79 | RIPK1 (0.55) | LMNARIPK1KDM4EL3MBTL1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012120053-A1 | BRANCHED OXATHIAZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS MEDICINE AND DRUG CONTAINING SAID DERIVATIVES AND USE THEREOF | SANOFI (FR) | 2012-09-13 | — | — | WO | disclosed |