Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 6/20 | 0.62 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.62 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16364002 | 0.90 | TRPC5 (0.77) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16364025 | 0.89 | TRPC5 (0.74) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16364028 | 0.88 | TRPC5 (0.73) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16076200 | 0.87 | TRPC5 (0.81) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| Hydrochloric Acid SCHEMBL16028751 | 0.86 | TRPC5 (0.79) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16028577 | 0.85 | TRPC5 (0.68) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL18834846 | 0.85 | TRPC5 (0.59) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16364254 | 0.85 | TRPC5 (0.60) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL19498669 | 0.84 | TRPC5 (0.68) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16076046 | 0.82 | TRPC5 (0.76) | TRPC5TRPC4TRPC1KCNH2PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014143799-A9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2014-12-24 | — | — | WO | disclosed |