Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.44 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16028192 | 0.90 | TRPC5 (0.55) | MAPK1USP2SMN1; SMN2HTTTSHR | |
| SCHEMBL16028973 | 0.86 | TRPC5 (0.55) | MAPK1USP2SMN1; SMN2HTTTSHR | |
| SCHEMBL30171214 | 0.86 | TRPC5 (0.55) | MAPK1USP2SMN1; SMN2HTTTSHR | |
| SCHEMBL16364237 | 0.85 | SMN1; SMN2 (0.56) | MAPK1USP2SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL16363859 | 0.84 | TRPC4 (0.51) | SMN1; SMN2HTTTSHRALDH1A1TP53 | |
| SCHEMBL18835222 | 0.83 | TRPC4 (0.43) | MAPK1SMN1; SMN2HTTTSHRALDH1A1 | |
| SCHEMBL16028226 | 0.83 | TRPC5 (0.56) | MAPK1SMN1; SMN2HTTTSHRTP53 | |
| SCHEMBL18834602 | 0.81 | MAPK1 (0.47) | MAPK1USP2SMN1; SMN2HTTTSHR | |
| SCHEMBL19375057 | 0.81 | MAOB (0.47) | TRPC4TRPC5KCNH2MAOAMAOB | |
| SCHEMBL16028345 | 0.80 | TRPC5 (0.60) | SMN1; SMN2HTTTSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014143799-A9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2014-12-24 | — | — | WO | disclosed |