Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132487 | 0.91 | THRB (0.58) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL29096365 | 0.83 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2545895 | 0.83 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9321905 | 0.79 | THRB (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL16378672 | 0.79 | THRB (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL379120 | 0.78 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL108325 | 0.78 | THRB (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL16588235 | 0.78 | THRB (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL14712313 | 0.78 | THRB (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL13950019 | 0.78 | THRB (0.53) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 583 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11874434-B2 | Ophthalmic devices comprising photochromic materials with reactive substituents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-01-16 | — | — | US | claimed |
| CN-116829995-A | Liquid crystal composition, cured film, polarizing plate, and image display device | 富士胶片株式会社 | 2023-09-29 | — | — | CN | claimed |
| EP-3673521-B1 | DIELECTRIC LAYER COMPRISING COPOLYMER WITH MESOGENIC UNITS | PPG IND OHIO INC (US) | 2023-08-09 | — | — | EP | claimed |
| US-11525087-B2 | Dielectric devices and methods of fabrication | PPG INDUSTRIES OHIO, INC. (US) | 2022-12-13 | — | — | US | claimed |
| EP-3268375-B1 | PHOTOCHROMIC THIENOCHROMENE COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2022-06-15 | — | — | EP | claimed |
| US-20220137262-A1 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS WITH REACTIVE SUBSTITUENTS | JOHNSON & JOHNSON VISION CARE (US) | 2022-05-05 | — | — | US | claimed |
| EP-3071576-B9 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2021-12-22 | — | — | EP | claimed |
| EP-3645540-B1 | SILOLE AND GERMOLE FUSED RING PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL LTD (IE) | 2021-11-03 | — | — | EP | claimed |
| EP-3071576-B1 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2021-08-18 | — | — | EP | claimed |
| US-20200263092-A1 | DIELECTRIC DEVICES AND METHODS OF FABRICATION | PPG INDUSTRIES OHIO, INC. | 2020-08-20 | — | — | US | claimed |
| US-20060226402-A1 | Ophthalmic devices comprising photochromic materials having extended PI-conjugated systems | KIM BEON-KYU | 2006-10-12 | — | — | US | claimed |
| US-20060228557-A1 | Photochromic materials having extended pi-conjugated systems and compositions and articles including the same | TRANSITIONS OPTICAL, INC. | 2006-10-12 | — | — | US | claimed |
| US-20060226401-A1 | Ophthalmic devices comprising photochromic materials with reactive substituents | JOHNSON & JOHNSON VISION CARE, INC. | 2006-10-12 | — | — | US | claimed |
| US-20060226400-A1 | Photochromic materials with reactive substituents | TRANSITIONS OPTICAL LIMITED (IE) | 2006-10-12 | — | — | US | claimed |
| US-20040186241-A1 | Photochromic ocular devices | TRANSITIONS OPTICAL, INC. | 2004-09-23 | — | — | US | claimed |
| CN-1529833-A | Photosensitive coloring composition, color filter using the same and method for producing the same | 昭和电工株式会社 | 2004-09-15 | — | — | CN | claimed |
| US-20040157140-A1 | Photosensitive coloring composition, color filter using the composition and method of producing the same | SHOWA DENKO K.K. (JP) | 2004-08-12 | — | — | US | claimed |
| US-6555028-B2 | Polymeric matrix compatibilized naphthopyrans | TRANSITIONS OPTICAL, INC. | 2003-04-29 | — | — | US | claimed |
| US-20010025948-A1 | Polymeric matrix compatibilized naphthopyrans | TRANSITIONS OPTICAL LIMITED (IE) | 2001-10-04 | — | — | US | claimed |
| EP-0358774-B1 | NOVEL SPIROOXAZINE COMPOUNDS | TORAY INDUSTRIES (JP) | 1995-10-25 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060228557-A1 | Photochromic materials having extended pi-conjugated systems and compositions and articles including the same | INCENP, PCNA, INTS6 | THRB 4882/4885TSHR 4793/4885ALDH1A1 2220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.