Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12247705 | 0.83 | MAPT (0.61) | CTSKMAPTCTSLCTSB | |
| SCHEMBL699601 | 0.83 | MAPT (0.61) | CTSKMAPTCTSLCTSB | |
| SCHEMBL22877388 | 0.83 | CTSK (0.48) | CTSKSIGMAR1MMP1MMP3MMP9 | |
| SCHEMBL5808813 | 0.82 | CTSK (0.65) | CTSKCTSLCTSBCTSS | |
| SCHEMBL4821212 | 0.81 | MAPT (0.66) | CTSKMAPTCTSLCTSB | |
| SCHEMBL5500108 | 0.80 | SYK (0.58) | CTSKMAPTCTSLCTSBMEN1 | |
| SCHEMBL17244777 | 0.80 | CTSK (0.43) | CTSKMAPTCTSLCTSBPAX8 | |
| SCHEMBL26384487 | 0.80 | SIGMAR1 (0.61) | SIGMAR1CYP3A4LMNAPKMCA1 | |
| SCHEMBL4961185 | 0.80 | SIGMAR1 (0.62) | SIGMAR1MMP1MMP3MMP9CYP3A4 | |
| SCHEMBL18474875 | 0.79 | KMT2A (0.56) | MAPTCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2816038-A1 | Hopo chelators | Lumiphore, Inc. (US) | 2014-12-24 | — | — | EP | disclosed |