SCHEMBL16365751

SCHEMBL16365751

COc1ccc(C2=NC(c3ccccc3Cl)(n3c(-c4ccccc4Cl)nc(-c4ccccc4Cl)c3-c3ccc(OC)c(OC)c3)N=C2c2ccccc2Cl)cc1OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.43
TP53 P04637 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
NPC1 O15118 2/20 0.43
ALDH1A1 P00352 2/20 0.43
RAB9A P51151 2/20 0.43
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PDE4A P27815 3/20 0.41
PIK3CD O00329 1/20 0.36
MAPT P10636 1/20 0.36
PDE10A Q9Y233 1/20 0.36
HTR7 P34969 1/20 0.35
ACACA Q13085 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPK10 P53779 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29895740 1.00 L3MBTL1 (0.43) L3MBTL1TP53MEN1KMT2ANPC1
SCHEMBL16355182 0.96 L3MBTL1 (0.41) L3MBTL1TP53MEN1KMT2ANPC1
SCHEMBL31734215 0.95 L3MBTL1 (0.43) L3MBTL1TP53MEN1KMT2ANPC1
SCHEMBL16355181 0.95 L3MBTL1 (0.43) L3MBTL1TP53MEN1KMT2ANPC1
SCHEMBL20464140 0.94 L3MBTL1 (0.44) L3MBTL1TP53MEN1KMT2ANPC1
SCHEMBL29895743 0.93 L3MBTL1 (0.43) L3MBTL1TP53MEN1KMT2ANPC1
SCHEMBL22710269 0.93 L3MBTL1 (0.43) L3MBTL1TP53MEN1KMT2ANPC1
SCHEMBL8089682 0.89 L3MBTL1 (0.45) L3MBTL1TP53MEN1KMT2ANPC1
SCHEMBL29991403 0.89 L3MBTL1 (0.42) L3MBTL1TP53MEN1KMT2ANPC1
SCHEMBL24924237 0.86 ERN1 (0.38) L3MBTL1TP53MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140374677-A1 COLORED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE EQUIPPED WITH SAME, ORGANIC EL DISPLAY DEVICE, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed