Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.77 |
| ▸ | NT5E | P21589 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.76 |
| ▸ | CA5A | P35218 | 1/20 | 0.74 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.59 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | HINT1 | P49773 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457018 | 1.00 | ADORA3 (0.77) | ADORA3NT5ELMNAHIF1ACA5A | |
| SCHEMBL4457021 | 1.00 | ADORA3 (0.77) | ADORA3NT5ELMNAHIF1ACA5A | |
| SCHEMBL13524754 | 1.00 | ADORA3 (0.77) | ADORA3NT5ELMNAHIF1ACA5A | |
| SCHEMBL1938203 | 0.89 | ADORA3 (0.80) | ADORA3NT5ELMNAHIF1ACA5A | |
| SCHEMBL4454099 | 0.89 | ADORA3 (0.80) | ADORA3NT5ELMNAHIF1ACA5A | |
| SCHEMBL12443734 | 0.89 | ADORA3 (0.80) | ADORA3NT5ELMNAHIF1ACA5A | |
| SCHEMBL8622533 | 0.88 | ADORA3 (0.78) | ADORA3NT5ELMNAHIF1ACA5A | |
| SCHEMBL29936666 | 0.88 | ADORA3 (0.78) | ADORA3NT5ELMNAHIF1ACA5A | |
| SCHEMBL19843952 | 0.88 | NT5E (0.81) | ADORA3NT5ELMNAHIF1ACA5A | |
| SCHEMBL17752649 | 0.88 | NT5E (0.81) | ADORA3NT5ELMNAHIF1ACA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014204856-A1 | FATTY ACID ANTICANCER DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2014-12-24 | — | — | WO | disclosed |