Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.77 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.77 |
| ▸ | NT5E | P21589 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12746240 | 1.00 | PNP (0.77) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL16366051 | 0.90 | PNP (0.74) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23474138 | 0.88 | PDE4D (0.82) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL15790476 | 0.88 | PDE4D (0.82) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL16573776 | 0.88 | ADORA3 (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL10427399 | 0.87 | PNP (0.70) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL10427400 | 0.87 | PNP (0.70) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL29479238 | 0.87 | PNP (0.70) | PNPLMNATP53HTTPDE4D | |
| Cladribine SCHEMBL3775 | 0.87 | PDE4D (1.00) | PNPLMNATP53HTTPDE4D | |
| Cladribine SCHEMBL21303677 | 0.87 | PDE4D (1.00) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014204856-A1 | FATTY ACID ANTICANCER DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2014-12-24 | — | — | WO | disclosed |