Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936424 | 0.86 | NQO2 (0.42) | DRD2DRD1PKMTSHRABCG2 | |
| SCHEMBL12446382 | 0.83 | NQO2 (0.46) | DRD2DRD1ABCG2NQO2CYP19A1 | |
| SCHEMBL25910897 | 0.83 | CHEK1 (0.40) | DRD2DRD1PKMTSHRABCG2 | |
| SCHEMBL17431881 | 0.80 | DRD2 (0.42) | DRD2DRD1PKMTSHRABCG2 | |
| SCHEMBL14950291 | 0.79 | AOC3 (0.44) | DRD2DRD1PKMTSHRABCG2 | |
| SCHEMBL7594061 | 0.79 | ABCG2 (0.55) | DRD2DRD1PKMTSHRABCG2 | |
| SCHEMBL12223372 | 0.79 | DRD2 (0.40) | DRD2DRD1PKMTSHRABCG2 | |
| SCHEMBL14929542 | 0.79 | DRD2 (0.40) | DRD2DRD1PKMTSHRABCG2 | |
| SCHEMBL12223409 | 0.79 | KDM4E (0.44) | DRD2DRD1NQO2CYP19A1GAA | |
| SCHEMBL20040527 | 0.79 | DRD2 (0.37) | DRD2DRD1PKMTSHRABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484842-B1 | HALOGEN-CONTAINING METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2023-05-03 | — | — | EP | disclosed |
| WO-2020018581-A1 | SYNTHESIS OF STRAIGHT-CHAIN LEPIDOPTERAN PHEROMONES THROUGH ONE- OR TWO- CARBON HOMOLOGATION OF FATTY ALKENES | PROVIVI, INC. (US) | 2020-01-23 | — | — | WO | disclosed |
| WO-2018013943-A1 | HALOGEN-CONTAINING METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-01-18 | — | — | WO | disclosed |
| US-9850268-B2 | Metathesis catalysts and methods thereof | TRUSTEES OF BOSTON COLLEGE (US) | 2017-12-26 | — | — | US | disclosed |
| US-9441059-B2 | Metathesis catalysts and methods thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-09-13 | — | — | US | disclosed |
| US-9085595-B2 | Tungsten oxo alkylidene complexes for Z selective olefin metathesis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-07-21 | — | — | US | disclosed |
| US-20140378637-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | NATIONAL SCIENCE FOUNDATION | 2014-12-25 | — | — | US | disclosed |