Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661389 | 0.86 | GPR84 (0.57) | GPR84HTR2AKDM4ECA2AKT1 | |
| SCHEMBL1661391 | 0.86 | GPR84 (0.57) | GPR84HTR2AKDM4ECA2AKT1 | |
| SCHEMBL4601998 | 0.86 | GPR84 (0.57) | GPR84HTR2AKDM4ECA2AKT1 | |
| SCHEMBL8416936 | 0.83 | GPR84 (0.62) | GPR84HTR2AKDM4ECA2IDO1 | |
| SCHEMBL12113330 | 0.83 | GPR84 (0.62) | GPR84HTR2AKDM4ECA2IDO1 | |
| SCHEMBL24247571 | 0.81 | GPR84 (0.59) | GPR84HTR2AKDM4ECA2IDO1 | |
| Hydrochloric Acid SCHEMBL6591093 | 0.80 | KDM4E (0.54) | GPR84HTR2AKDM4ECA2LMNA | |
| Hydrochloric Acid SCHEMBL27373422 | 0.80 | KDM4E (0.54) | GPR84HTR2AKDM4ECA2LMNA | |
| Hydrochloric Acid SCHEMBL27373423 | 0.80 | KDM4E (0.54) | GPR84HTR2AKDM4ECA2LMNA | |
| SCHEMBL5018864 | 0.80 | GPR84 (0.67) | GPR84HTR2AKDM4ECA2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014204856-A1 | FATTY ACID ANTICANCER DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2014-12-24 | — | — | WO | disclosed |