Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12113330 | 0.83 | GPR84 (0.62) | GPR84HTR2AIDO1CA2KEAP1 | |
| SCHEMBL8416936 | 0.83 | GPR84 (0.62) | GPR84HTR2AIDO1CA2KEAP1 | |
| SCHEMBL4601998 | 0.83 | GPR84 (0.57) | GPR84HTR2AIDO1CA2KEAP1 | |
| SCHEMBL1661389 | 0.83 | GPR84 (0.57) | GPR84HTR2AIDO1CA2KEAP1 | |
| SCHEMBL1661391 | 0.83 | GPR84 (0.57) | GPR84HTR2AIDO1CA2KEAP1 | |
| SCHEMBL16366297 | 0.81 | GPR84 (0.59) | GPR84HTR2AIDO1CA2KEAP1 | |
| SCHEMBL17306338 | 0.80 | ALDH1A1 (0.56) | GPR84HTR2AIDO1CA2KDM4E | |
| SCHEMBL19846989 | 0.80 | ALDH1A1 (0.56) | GPR84HTR2AIDO1CA2KDM4E | |
| SCHEMBL24445574 | 0.80 | SCN9A (0.57) | GPR84HTR2AIDO1CA2KDM4E | |
| 1-Methyltryptophan SCHEMBL14202956 | 0.80 | MAPT (0.71) | GPR84HTR2ACA2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3954369-A1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | Lumos Pharma, Inc. (US) | 2022-02-16 | — | — | EP | disclosed |