Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.66 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | PARP14 | Q460N5 | 15/20 | 0.56 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16366312 | 0.88 | PDE10A (0.54) | PARP1PDE10APARP14PARP2 | |
| SCHEMBL1946020 | 0.79 | PARP1 (1.00) | PARP1PARP14 | |
| SCHEMBL1945766 | 0.79 | PARP1 (1.00) | PARP1PARP14 | |
| SCHEMBL3443321 | 0.79 | PARP1 (1.00) | PARP1PARP14 | |
| SCHEMBL30417469 | 0.79 | PARP1 (1.00) | PARP1PARP14 | |
| SCHEMBL30090665 | 0.79 | PARP1 (1.00) | PARP1PARP14 | |
| Bromide SCHEMBL1944264 | 0.78 | PARP1 (0.98) | PARP1PARP14 | |
| Bromide SCHEMBL1944266 | 0.78 | PARP1 (0.98) | PARP1PARP14 | |
| Hydrochloric Acid SCHEMBL1946669 | 0.78 | PARP1 (0.98) | PARP1PARP14 | |
| Hydrochloric Acid SCHEMBL1946668 | 0.78 | PARP1 (0.98) | PARP1PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014204856-A1 | FATTY ACID ANTICANCER DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2014-12-24 | — | — | WO | disclosed |