Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 11/20 | 0.86 |
| ▸ | SRC | P12931 | 8/20 | 0.86 |
| ▸ | LCK | P06239 | 4/20 | 0.82 |
| ▸ | PKMYT1 | Q99640 | 3/20 | 0.82 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.82 |
| ▸ | EGFR | P00533 | 2/20 | 0.82 |
| ▸ | FYN | P06241 | 2/20 | 0.82 |
| ▸ | CSF1R | P07333 | 2/20 | 0.82 |
| ▸ | YES1 | P07947 | 2/20 | 0.82 |
| ▸ | LYN | P07948 | 2/20 | 0.82 |
| ▸ | RET | P07949 | 2/20 | 0.82 |
| ▸ | HCK | P08631 | 2/20 | 0.82 |
| ▸ | KIT | P10721 | 2/20 | 0.82 |
| ▸ | BCR | P11274 | 2/20 | 0.82 |
| ▸ | BRAF | P15056 | 2/20 | 0.82 |
| ▸ | EPHA1 | P21709 | 2/20 | 0.82 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.82 |
| ▸ | EPHA3 | P29320 | 2/20 | 0.82 |
| ▸ | EPHA8 | P29322 | 2/20 | 0.82 |
| ▸ | EPHB2 | P29323 | 2/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22861837 | 0.99 | ABL1 (0.88) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL17620522 | 0.96 | ABL1 (0.93) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL25918909 | 0.94 | ABL1 (0.90) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL17663528 | 0.94 | ABL1 (0.86) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL14670790 | 0.93 | ABL1 (0.83) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL20339396 | 0.93 | ABL1 (0.99) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL31114216 | 0.93 | ABL1 (0.99) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL16582217 | 0.93 | ABL1 (0.85) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL16907384 | 0.92 | ABL1 (0.82) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL16898212 | 0.92 | ABL1 (1.00) | ABL1SRCLCKPKMYT1EPHB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019173224-A1 | DEUTERATED COMPOUNDS AND CHIMERAS AND USES THEREOF | BIOTHERYX, INC. (US) | 2019-09-12 | — | — | WO | disclosed |
| WO-2014204856-A1 | FATTY ACID ANTICANCER DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2014-12-24 | — | — | WO | disclosed |