Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 11/20 | 0.93 |
| ▸ | SRC | P12931 | 8/20 | 0.93 |
| ▸ | LCK | P06239 | 4/20 | 0.85 |
| ▸ | PKMYT1 | Q99640 | 3/20 | 0.85 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.85 |
| ▸ | EGFR | P00533 | 2/20 | 0.85 |
| ▸ | FYN | P06241 | 2/20 | 0.85 |
| ▸ | CSF1R | P07333 | 2/20 | 0.85 |
| ▸ | YES1 | P07947 | 2/20 | 0.85 |
| ▸ | LYN | P07948 | 2/20 | 0.85 |
| ▸ | RET | P07949 | 2/20 | 0.85 |
| ▸ | HCK | P08631 | 2/20 | 0.85 |
| ▸ | KIT | P10721 | 2/20 | 0.85 |
| ▸ | BCR | P11274 | 2/20 | 0.85 |
| ▸ | BRAF | P15056 | 2/20 | 0.85 |
| ▸ | EPHA1 | P21709 | 2/20 | 0.85 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.85 |
| ▸ | EPHA3 | P29320 | 2/20 | 0.85 |
| ▸ | EPHA8 | P29322 | 2/20 | 0.85 |
| ▸ | EPHB2 | P29323 | 2/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25918909 | 0.98 | ABL1 (0.90) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL22861837 | 0.97 | ABL1 (0.88) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL16898227 | 0.96 | ABL1 (1.00) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL16898682 | 0.96 | ABL1 (1.00) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL16898725 | 0.96 | ABL1 (1.00) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL16898212 | 0.96 | ABL1 (1.00) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL31114216 | 0.96 | ABL1 (0.99) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL20339396 | 0.96 | ABL1 (0.99) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL16366394 | 0.96 | ABL1 (0.86) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL14670708 | 0.95 | ABL1 (0.85) | ABL1SRCLCKPKMYT1EPHB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180021443-A1 | LOW MOLECULAR WEIGHT POLYETHYLENE GLYCOL DRUG CONJUGATES HAVING IMPROVED DRUG BIOLOGICAL ACTIVITY | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2018-01-25 | — | — | US | disclosed |
| US-9789198-B2 | Low molecular weight polyethylene glycol drug conjugates having improved drug biological activity | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2017-10-17 | — | — | US | disclosed |
| EP-3006050-A1 | LOW MOLECULAR WEIGHT POLYETHYLENE GLYCOL DRUG CONJUGATES HAVING IMPROVED DRUG BIOLOGICAL ACTIVITY | Jenkem Technology Co. Ltd. (Tianjin) (CN) | 2016-04-13 | — | — | EP | disclosed |
| US-20160082117-A1 | LOW MOLECULAR WEIGHT POLYETHYLENE GLYCOL DRUG CONJUGATES HAVING IMPROVED DRUG BIOLOGICAL ACTIVITY | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180021443-A1 | LOW MOLECULAR WEIGHT POLYETHYLENE GLYCOL DRUG CONJUGATES HAVING IMPROVED DRUG BIOLOGICAL ACTIVITY | FCGR2A, FCGR1A, FCER2 | ABL1 1768/4885SRC 2170/4885LCK 3287/4885 |
| US-20160082117-A1 | LOW MOLECULAR WEIGHT POLYETHYLENE GLYCOL DRUG CONJUGATES HAVING IMPROVED DRUG BIOLOGICAL ACTIVITY | FCGR2A, FCGR1A, FCER2 | ABL1 1768/4885SRC 2170/4885LCK 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.