Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 11/20 | 0.99 |
| ▸ | SRC | P12931 | 8/20 | 0.99 |
| ▸ | LCK | P06239 | 4/20 | 0.80 |
| ▸ | PKMYT1 | Q99640 | 3/20 | 0.80 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.80 |
| ▸ | EGFR | P00533 | 2/20 | 0.80 |
| ▸ | FYN | P06241 | 2/20 | 0.80 |
| ▸ | CSF1R | P07333 | 2/20 | 0.80 |
| ▸ | YES1 | P07947 | 2/20 | 0.80 |
| ▸ | LYN | P07948 | 2/20 | 0.80 |
| ▸ | RET | P07949 | 2/20 | 0.80 |
| ▸ | HCK | P08631 | 2/20 | 0.80 |
| ▸ | KIT | P10721 | 2/20 | 0.80 |
| ▸ | BCR | P11274 | 2/20 | 0.80 |
| ▸ | BRAF | P15056 | 2/20 | 0.80 |
| ▸ | EPHA1 | P21709 | 2/20 | 0.80 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.80 |
| ▸ | EPHA3 | P29320 | 2/20 | 0.80 |
| ▸ | EPHA8 | P29322 | 2/20 | 0.80 |
| ▸ | EPHB2 | P29323 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114216 | 1.00 | ABL1 (0.99) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL16898682 | 0.99 | ABL1 (1.00) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL16898212 | 0.99 | ABL1 (1.00) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL16898227 | 0.99 | ABL1 (1.00) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL16898725 | 0.99 | ABL1 (1.00) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL17620522 | 0.96 | ABL1 (0.93) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL25918909 | 0.94 | ABL1 (0.90) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL25247576 | 0.93 | ABL1 (0.89) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL31672273 | 0.93 | ABL1 (0.89) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL22861837 | 0.93 | ABL1 (0.88) | ABL1SRCLCKPKMYT1EPHB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11913944-B2 | Photoaffinity probes | PROMEGA CORPORATION (US) | 2024-02-27 | — | — | US | disclosed |
| EP-3562823-B1 | FUNCTIONALIZED NANOLUC INHIBITORS | PROMEGA CORP (US) | 2023-02-08 | — | — | EP | disclosed |
| US-20200340982-A1 | PHOTOAFFINITY PROBES | PROMEGA CORPORATION | 2020-10-29 | — | — | US | disclosed |
| US-10815247-B2 | Functionalized NANOLUC inhibitors | PROMEGA CORPORATION (US) | 2020-10-27 | — | — | US | disclosed |
| EP-3562823-A1 | FUNCTIONALIZED NANOLUC INHIBITORS | Promega Corporation (US) | 2019-11-06 | — | — | EP | disclosed |
| US-20180222916-A1 | FUNCTIONALIZED NANOLUC INHIBITORS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2018-08-09 | — | — | US | disclosed |
| WO-2018125992-A1 | FUNCTIONALIZED NANOLUC INHIBITORS | PROMEGA CORPORATION (US) | 2018-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10815247-B2 | Functionalized NANOLUC inhibitors | RNGTT, LUC7L2, GUSB | ABL1 3186/4885SRC 2979/4885LCK 4231/4885 |
| US-20180222916-A1 | FUNCTIONALIZED NANOLUC INHIBITORS | RNGTT, LUC7L2, GUSB | ABL1 3186/4885SRC 2979/4885LCK 4231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.