SCHEMBL16366993

SCHEMBL16366993

CCOC(=O)OC1=C(c2cc(CC)ccc2C)C(=O)NC12CCC(OC)CC2

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ACACB O00763 13/20 0.47
ACACA Q13085 13/20 0.47
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
BACE1 P56817 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GRM1 Q13255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Spirotetramat SCHEMBL27350845 0.91 ACACB (0.49) ACACBACACAMEN1KMT2ASMN1; SMN2
Spirotetramat SCHEMBL12022413 0.91 ACACB (0.49) ACACBACACAMEN1KMT2ASMN1; SMN2
Spirotetramat SCHEMBL337030 0.91 ACACB (0.49) ACACBACACAMEN1KMT2ASMN1; SMN2
Spirotetramat SCHEMBL14855635 0.91 ACACB (0.49) ACACBACACAMEN1KMT2ASMN1; SMN2
Spirotetramat SCHEMBL26389 0.91 ACACB (0.49) ACACBACACAMEN1KMT2ASMN1; SMN2
Spirotetramat SCHEMBL2584908 0.90 ACACB (0.49) ACACBACACAMEN1KMT2ASMN1; SMN2
SCHEMBL12778773 0.89 ACACB (0.47) ACACBACACAGABRA1GABRB2BACE1
SCHEMBL12564504 0.85 ACACB (0.57) ACACBACACABACE1
SCHEMBL2850592 0.85 ACACB (0.52) ACACBACACAMEN1KMT2A
SCHEMBL6371037 0.84 ACACB (0.48) ACACBACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9056853-B2 N-Thio-anthranilamid compounds and their use as pesticides BASF SE (DE) 2015-06-16 US disclosed
US-20140378458-A1 N-Thio-anthranilamid compounds and their use as pesticides BASF SE (DE) 2014-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140378458-A1 N-Thio-anthranilamid compounds and their use as pesticides NAT1, AAAS, ACHE ACACB 632/4885ACACA 79/4885GABRA1 2553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.