Spirotetramat

Spirotetramat

SCHEMBL337030

CCOC(=O)OC1=C(c2cc(C)ccc2C)C(=O)NC12CCC(OC)CC2

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACACB O00763 13/20 0.49
ACACA Q13085 13/20 0.49
THRB P10828 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
USP2 O75604 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
MDM2 Q00987 1/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Spirotetramat SCHEMBL27350845 1.00 ACACB (0.49) ACACBACACATHRBMEN1KMT2A
Spirotetramat SCHEMBL12022413 1.00 ACACB (0.49) ACACBACACATHRBMEN1KMT2A
Spirotetramat SCHEMBL26389 1.00 ACACB (0.49) ACACBACACATHRBMEN1KMT2A
Spirotetramat SCHEMBL14855635 1.00 ACACB (0.49) ACACBACACATHRBMEN1KMT2A
Spirotetramat SCHEMBL2584908 0.99 ACACB (0.49) ACACBACACATHRBMEN1KMT2A
SCHEMBL2850592 0.94 ACACB (0.52) ACACBACACATHRBMEN1KMT2A
SCHEMBL3902979 0.92 ACACB (0.41) ACACBACACATHRBMEN1KMT2A
SCHEMBL15894937 0.92 ACACB (0.51) ACACBACACATHRB
SCHEMBL18393305 0.92 ACACB (0.51) ACACBACACATHRB
SCHEMBL16366993 0.91 ACACB (0.47) ACACBACACAMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 781 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12163142-B2 Methods for manufacturing plant messenger packs FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2024-12-10 US claimed
US-11827897-B2 Agricultural compositions and related methods FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2023-11-28 US claimed
US-20220064661-A1 AGRICULTURAL COMPOSITIONS AND RELATED METHODS FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2022-03-03 US claimed
EP-2213168-A1 Pesticidal combination of active agents Bayer CropScience AG (DE) 2010-08-04 EP claimed
US-20100137373-A1 PESTICIDAL COMPOSITION COMPRISING A STRIGOLACTONE DERIVATIVE AND AN INSECTICIDE COMPOUND BAYER INTELLECTUAL PROPERTY GMBH (DE) 2010-06-03 US claimed
EP-2157857-A2 PESTICIDAL COMPOSITION COMPRISING A STRIGOLACTONE DERIVATIVE AND AN INSECTICIDE COMPOUND Bayer CropScience SA (FR) 2010-03-03 EP claimed
US-20100048497-A1 INSECTICIDAL ACTIVE INGREDIENT COMBINATIONS (FORMONONETINS + INSECTICIDES) BAYER CROPSCIENCE AG (DE) 2010-02-25 US claimed
US-20100048404-A1 PESTICIDAL COMPOSITION COMPRISING A SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND AN INSECTICIDE COMPOUND BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-02-25 US claimed
EP-2107871-A2 INSECTICIDAL ACTIVE INGREDIENT COMBINATIONS (FORMONONETINS + INSECTICIDES) Bayer CropScience AG (DE) 2009-10-14 EP claimed
WO-2009012909-A2 INSECTICIDAL ACTIVE SUBSTANCE COMBINATIONS (GENESTEIN + INSECTICIDES) BAYER CROPSCIENCE AG (DE) 2009-01-29 WO claimed
WO-2008152091-A2 PESTICIDAL COMPOSITION COMPRISING A STRIGOLACTONE DERIVATIVE AND AN INSECTICIDE COMPOUND BAYER CROPSCIENCE SA (FR) 2008-12-18 WO claimed
EP-2000029-A1 Insecticide and fungicide active agent combinations Bayer CropScience AG (DE) 2008-12-10 EP claimed
US-20080293566-A1 Active Substance Combinations BAYER CROPSCIENCE AG (DE) 2008-11-27 US claimed
WO-2008064778-A2 INSECTICIDAL ACTIVE INGREDIENT COMBINATIONS (FORMONONETINS + INSECTICIDES) BAYER CROPSCIENCE AG (DE) 2008-06-05 WO claimed
EP-1876897-A2 ACTIVE SUBSTANCE COMBINATIONS Bayer CropScience AG (DE) 2008-01-16 EP claimed
WO-2006114212-A2 COMBINATIONS OF PESTICIDAL ACTIVE SUBSTANCE COMBINATIONS BAYER CROPSCIENCE AG (DE) 2006-11-02 WO claimed
US-20250388630-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC (US) 2025-12-25 US disclosed
US-20250318529-A1 METHOD FOR MOSQUITO CONTROL SYNGENTA CROP PROTECTION AG (CH) 2025-10-16 US disclosed
WO-2005016001-A1 SAFENER BASED ON AROMATIC-ALIPHATIC CARBOXYLIC ACID DERIVATIVES BAYER CROPSCIENCE GMBH (DE) 2005-02-24 WO disclosed
US-20050037922-A1 Use of hydroxyaromatics as safeners BAYER CROPSCIENCE GMBH (DE) 2005-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048404-A1 PESTICIDAL COMPOSITION COMPRISING A SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND AN INSECTICIDE COMPOUND CYP51A1, DDT, ACHE ACACB 1325/4885ACACA 2215/4885THRB 1409/4885
US-20080293566-A1 Active Substance Combinations AADAC, CHIA, CAT ACACB 244/4885ACACA 217/4885THRB 3417/4885
US-20100048497-A1 INSECTICIDAL ACTIVE INGREDIENT COMBINATIONS (FORMONONETINS + INSECTICIDES) ACHE, ACAT1, CIAPIN1 ACACB 21/4885ACACA 16/4885THRB 4429/4885
US-20250318529-A1 METHOD FOR MOSQUITO CONTROL SGMS2, MGAM2, SGMS1 ACACB 198/4885ACACA 1105/4885THRB 4612/4885
US-20050037922-A1 Use of hydroxyaromatics as safeners CBR1, CYP8B1, AHR ACACB 701/4885ACACA 482/4885THRB 896/4885
US-20100137373-A1 PESTICIDAL COMPOSITION COMPRISING A STRIGOLACTONE DERIVATIVE AND AN INSECTICIDE COMPOUND PTMS, STK39, CYP17A1 ACACB 2609/4885ACACA 2738/4885THRB 191/4885
US-20250388630-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA MAX, SEC62, GHITM ACACB 2773/4885ACACA 3876/4885THRB 998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.