Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCH | P24723 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14201357 | 0.92 | TSHR (0.41) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL13484061 | 0.90 | TSHR (0.43) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10595415 | 0.90 | MEN1 (0.32) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10021094 | 0.87 | MEN1 (0.41) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL3888267 | 0.86 | TSHR (0.33) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL23658245 | 0.83 | TSHR (0.40) | MEN1THRBKMT2AALDH1A1TSHR | |
| SCHEMBL996934 | 0.83 | TSHR (0.40) | MEN1THRBKMT2AALDH1A1TSHR | |
| SCHEMBL17191748 | 0.83 | TSHR (0.40) | MEN1THRBKMT2AALDH1A1TSHR | |
| SCHEMBL20359349 | 0.83 | TSHR (0.40) | MEN1THRBKMT2AALDH1A1TSHR | |
| SCHEMBL14910493 | 0.83 | TSHR (0.40) | MEN1THRBKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150011723-A1 | ORGANOSILICON COMPOUNDS AND THEIR USE THEREOF FOR PRODUCING HYDROPHILIC SURFACES | WACKER CHEMIE AG (DE) | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011723-A1 | ORGANOSILICON COMPOUNDS AND THEIR USE THEREOF FOR PRODUCING HYDROPHILIC SURFACES | EPCAM, SORD, ILK | HTT 3018/4885MEN1 1393/4885THRB 4578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.