Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301563 | 0.86 | TSHR (0.53) | TSHRALDH1A1THRB | |
| SCHEMBL9301359 | 0.86 | TSHR (0.53) | TSHRALDH1A1THRB | |
| SCHEMBL9302380 | 0.86 | TSHR (0.53) | TSHRALDH1A1THRB | |
| SCHEMBL977527 | 0.78 | TSHR (0.55) | TSHRALDH1A1THRB | |
| SCHEMBL2772530 | 0.78 | TSHR (0.55) | TSHRALDH1A1THRB | |
| SCHEMBL3319370 | 0.77 | TSHR (0.75) | TSHRALDH1A1THRB | |
| SCHEMBL2334126 | 0.77 | TSHR (0.58) | TSHRALDH1A1THRB | |
| SCHEMBL393244 | 0.76 | TSHR (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL9302242 | 0.76 | TSHR (0.56) | TSHRALDH1A1THRB | |
| SCHEMBL9303597 | 0.76 | TSHR (0.56) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944742-B2 | Organo-modified silicone polymers | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-9890234-B2 | Organo-modified silicone polymers and hydrogels comprising the same | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-02-13 | — | — | US | disclosed |
| US-20150011671-A1 | ORGANO-MODIFIED SILICONE POLYMERS AND HYDROGELS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2015-01-08 | — | — | US | disclosed |
| US-20150011788-A1 | ORGANO-MODIFIED SILICONE POLYMERS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2015-01-08 | — | — | US | disclosed |
| US-20150011788-A1 | ORGANO-MODIFIED SILICONE POLYMERS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2015-01-08 | — | — | US | disclosed |
| US-20150011671-A1 | ORGANO-MODIFIED SILICONE POLYMERS AND HYDROGELS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011788-A1 | ORGANO-MODIFIED SILICONE POLYMERS | PWWP2B, LTN1, LEO1 | TSHR 3752/4885ALDH1A1 1156/4885THRB 1109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.