Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | TGM2 | P21980 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15543609 | 0.88 | DRD4 (0.42) | DRD4SIGMAR1CYP19A1TGM2POLB | |
| SCHEMBL16367420 | 0.88 | DRD4 (0.42) | DRD4SIGMAR1CYP19A1TGM2POLB | |
| SCHEMBL15607911 | 0.85 | CYP19A1 (0.40) | DRD4SIGMAR1CYP19A1TGM2POLB | |
| SCHEMBL16367401 | 0.85 | CYP19A1 (0.40) | DRD4SIGMAR1CYP19A1TGM2POLB | |
| SCHEMBL15544899 | 0.84 | CYP19A1 (0.39) | DRD4SIGMAR1CYP19A1TGM2POLB | |
| SCHEMBL15545208 | 0.80 | BCHE (0.38) | DRD4SIGMAR1CYP19A1ALDH1A1CYP1A2 | |
| SCHEMBL15544471 | 0.77 | CYP19A1 (0.40) | DRD4SIGMAR1CYP19A1TGM2MAPT | |
| SCHEMBL15543953 | 0.74 | CYP19A1 (0.37) | DRD4SIGMAR1CYP19A1TGM2ALDH1A1 | |
| SCHEMBL19419498 | 0.73 | CYP19A1 (0.37) | CYP19A1POLB | |
| SCHEMBL16367312 | 0.72 | ALDH1A1 (0.39) | CYP19A1POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150010474-A1 | Compounds And Methods For Selective Imaging And/Or Ablation | AUCKLAND UNISERVICES LTD (NL) | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150010474-A1 | Compounds And Methods For Selective Imaging And/Or Ablation | CBR1, CBR3, BLVRB | DRD4 3149/4885SIGMAR1 803/4885CYP19A1 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.