SCHEMBL1636901

SCHEMBL1636901

Cc1csc(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethoxycarbonyl Group SCHEMBL28776539 0.77 DAO (0.32)
SCHEMBL422305 0.71
SCHEMBL2016588 0.71 CES2 (0.43)
SCHEMBL9773308 0.69 DAO (0.44)
SCHEMBL40746 0.69
SCHEMBL7646689 0.68 MLYCD (0.38)
SCHEMBL8587840 0.65
SCHEMBL2655111 0.65
SCHEMBL4097413 0.65
SCHEMBL855652 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240383856-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-11-21 US claimed
CN-118221735-A Synthesis method of bis (4-methyl-2-thienyl) phosphorus chloride 浙江九洲药业股份有限公司 2024-06-21 CN claimed
CN-105111415-B Polythiophene derivative with side chain containing naphthalene groups and preparing method and application of polythiophene derivative 天津理工大学 2017-05-03 CN claimed
CN-102459166-B Azetidinyl diamides as monoacylglycerol lipase inhibitors JANSSEN PHARMACEUTICA NV 2015-03-25 CN claimed
US-20260014261-A1 TARGETED PROTEIN MODIFICATION WEATHERWAX BIOTECHNOLOGIES CORP (US) 2026-01-15 US disclosed
CN-118221735-A Synthesis method of bis (4-methyl-2-thienyl) phosphorus chloride 浙江九洲药业股份有限公司 2024-06-21 CN disclosed
CN-118221735-A Synthesis method of bis (4-methyl-2-thienyl) phosphorus chloride 浙江九洲药业股份有限公司 2024-06-21 CN disclosed
WO-2024112611-A1 TARGETED PROTEIN MODIFICATION WEATHERWAX BIOTECHNOLOGIES CORPORATION (US) 2024-05-30 WO disclosed
US-20230312481-A1 SUBSTITUTED (PHTHALAZIN-1-YLMETHYL)UREAS, SUBSTITUTED N-(PHTHALAZIN-1-YLMETHYL)AMIDES, AND ANALOGUES THEREOF ARBUTUS BIOPHARMA CORP (CA) 2023-10-05 US disclosed
WO-2023110138-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2023-06-22 WO disclosed
WO-2023275337-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2023-01-05 WO disclosed
WO-2023275333-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2023-01-05 WO disclosed
EP-1196428-B1 11-BETA-ARYL-17,17-SPIROTHIOLANE-SUBSTITUTED STEROIDS RES TRIANGLE INST (US) 2004-09-22 EP disclosed
WO-2004058767-A1 PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP TAISHO PHARMACEUTICAL CO., LTD. (JP) 2004-07-15 WO disclosed
EP-0987567-B1 A sulfur-containing (thio)ether (co)polymer and a use thereof MITSUI CHEMICALS INC (JP) 2004-04-07 EP disclosed
US-6320020-B1 POLYMER OR COPOLYMER CONTAINING A SULFUR ATOM WHOSE PRINCIPAL BACKBONE COMPRISES ETHER AND/OR THIOETHER BONDS; OPTICAL DISK SUBSTRATE; A LIQUID-CRYSTAL PLASTIC SUBSTRATE; VARIOUS OPTICAL LENSES INCLUDING AN EYEGLASS; AND AN LED SEALING COAT. MITSUI CHEMICALS, INC. (JP) 2001-11-20 US disclosed
US-6043235-A 11β-aryl-17, 17-spirothiolane-substituted steroids RESEARCH TRIANGLE INSTITUTE (US) 2000-03-28 US disclosed
EP-0987567-A1 A sulfur-containing (thio)ether (co)polymer and a use thereof Mitsui Chemicals, Inc. (JP) 2000-03-22 EP disclosed
EP-0942909-A1 BICYCLIC AMINE DERIVATIVES ZENECA LIMITED (GB) 1999-09-22 EP disclosed
WO-1998022463-A1 BICYCLIC AMINE DERIVATIVES ZENECA LIMITED (GB) 1998-05-28 WO disclosed