Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15018540 | 1.00 | NPC1 (0.36) | NPC1RAB9AMAPTALDH1A1TSHR | |
| SCHEMBL15018539 | 1.00 | NPC1 (0.36) | NPC1RAB9AMAPTALDH1A1TSHR | |
| SCHEMBL20853560 | 0.99 | MAPT (0.38) | NPC1RAB9AMAPTALDH1A1TSHR | |
| SCHEMBL20853561 | 0.99 | MAPT (0.38) | NPC1RAB9AMAPTALDH1A1TSHR | |
| SCHEMBL15037506 | 0.99 | MAPT (0.38) | NPC1RAB9AMAPTALDH1A1TSHR | |
| SCHEMBL20853540 | 0.97 | TSHR (0.36) | NPC1RAB9AMAPTALDH1A1TSHR | |
| SCHEMBL15037477 | 0.97 | TSHR (0.36) | NPC1RAB9AMAPTALDH1A1TSHR | |
| SCHEMBL20853539 | 0.97 | TSHR (0.36) | NPC1RAB9AMAPTALDH1A1TSHR | |
| SCHEMBL15018422 | 0.93 | MEN1 (0.36) | RAB9AMAPTALDH1A1TSHRLMNA | |
| SCHEMBL16369060 | 0.93 | MEN1 (0.36) | RAB9AMAPTALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791250-B1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | OREAL (FR) | 2019-04-03 | — | — | EP | disclosed |
| US-9226883-B2 | Particular azomethine direct dyes, dye composition comprising at least one such compound, implementation process therefore and use thereof | L'OREAL (FR) | 2016-01-05 | — | — | US | disclosed |
| US-9226883-B2 | Particular azomethine direct dyes, dye composition comprising at least one such compound, implementation process therefore and use thereof | L'OREAL (FR) | 2016-01-05 | — | — | US | disclosed |
| US-20150000688-A1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | L'OREAL (FR) | 2015-01-01 | — | — | US | disclosed |
| US-20150000688-A1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | L'OREAL (FR) | 2015-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150000688-A1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | KRT18, IK, MKI67 | NPC1 4361/4885RAB9A 4275/4885MAPT 755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.