Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20853561 | 1.00 | MAPT (0.38) | MAPTNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL15037506 | 1.00 | MAPT (0.38) | MAPTNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL16369057 | 0.99 | NPC1 (0.36) | MAPTNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL15018539 | 0.99 | NPC1 (0.36) | MAPTNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL15018540 | 0.99 | NPC1 (0.36) | MAPTNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL20853539 | 0.96 | TSHR (0.36) | MAPTNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL15037477 | 0.96 | TSHR (0.36) | MAPTNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL20853540 | 0.96 | TSHR (0.36) | MAPTNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL15018422 | 0.92 | MEN1 (0.36) | MAPTRAB9AALDH1A1TSHRLMNA | |
| SCHEMBL16369060 | 0.92 | MEN1 (0.36) | MAPTRAB9AALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791250-B1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | OREAL (FR) | 2019-04-03 | — | — | EP | claimed |
| EP-2791250-B1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | OREAL (FR) | 2019-04-03 | — | — | EP | disclosed |